2020年12月24日 星期四

兩種mRNA疫苗臨床試驗結果之比較

 洛杉磯時報2020/12/15報導Moderna及Pfizer兩種新冠疫苗的比較

Pfizer疫苗對亞裔美國人的效果是74.4% 

Moderna疫苗對亞裔美國人有效率是100%

在預防嚴重的Covid-19方面,Moderna是100%,Pfizer是66.4%

兩者共同的副作用是疲倦、頭痛、肌肉痛、發冷和關節痛,Moderna試驗報告的人數稍多


https://www.latimes.com/science/story/2020-12-15/how-the-covid-19-vaccines-from-moderna-and-pfizer-compare-head-to-head

All five of the people in the Moderna trial who developed COVID-19 after receiving the vaccine were white. As a result,  the Moderna vaccine was 100% effective in Black, Latino and Asian Americans, as well as in people with mixed racial backgrounds. 

In its Phase 3 trial, the Pfizer vaccine was 100% effective for Black study participants and 94.5% effective for Latino participants, slightly below the 94.7% effectiveness for white subjects. In addition, it was 74.4% effective in Asian Americans, and 100% effective in Native Americans and Pacific Islanders.

The Moderna vaccine was 100% effective at preventing cases of severe COVID-19. 

The Pfizer vaccine was 66.4% effective at preventing cases of severe COVID-19. 

The most common side effects for both vaccines were fatigue, headache, muscle pain, chills and joint pain. However, these were reported more often in the Moderna trial than the Pfizer trial.


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